This year, I have been awed by the strength of our community. I think 2014 will be known as the year we effected change at every turn in clinical trials, on Capitol Hill, at the FDA, in doctors’ offices. And we did it as a community. Now it’s time to tackle the next challenge.
In 2015, PPMD will invest $600,000 to further the advancement of combination therapies in Duchenne. To start, we need to raise $400,000 this holiday season. That sounds big, I know, but thanks to our partners, it’s within reach—every gift today goes twice as far thanks to two Duchenne foundations that, like us, believe in the importance of combined therapies to treat this horrible disease.
Right now, we have multiple drugs that address different aspects of Duchenne advancing in clinical trials. We recognize that the best results will likely be achieved by using these drugs in combination. Combination therapeutics, after all, have been the most effective approach for diseases such as AIDS and cancer. In addition, combination therapies have the potential to benefit every person with Duchenne, regardless of mutation.
So we need to prepare now for the next stage of Duchenne research by systematically trying drugs together, first in animal studies and then in human trials. We also need to understand how regulators will view combination therapies and lay the groundwork now for rapid testing and approval of combinations.
Combination therapeutics are a crucial part of the fight to end Duchenne, and your gift will help us move this critical research forward. If we can raise $200,000 this month, we’ll reach the $400,000 we need thanks to generous matches from Rally for Ryan and Cure Dale’s Duchenne. We’re thrilled that these amazing foundations understand how collaborative effort will push forward our combination therapies.
We see strength when we combine forces voices, actions, dollars and work together. Your gift makes us stronger.
P.S. Your online donation will be doubled thanks to the generous support of foundations that, like PPMD, believe in the idea of combination therapeutics to end Duchenne. Double your gift now!