My grandson, now 4years old, was diagnosed with DMD about a year and a half ago. There is no known history of MD in the family. My daughter tested positive as a carrier. Does anyone know whether or not being a carrier can be a fluke, or can it skip a couple of generations? I also wonder how other mothers that are carriers, deal with the guilt of passing this to their child? My daughter has massive, massive guilt over passing DMD to her son.