John D. Porter, PhD's Blog – December 2015 Archive (2)

A New Dog Model for Drug Development in Duchenne

Photograph: Chris Kench/ via The Guardian



Added by John D. Porter, PhD on December 21, 2015 at 11:03am — No Comments

Dystrophin Mutations Affect Not Only Existing Muscle Fibers, but Satellite Cells As Well

A recent paper by Michael Rudnicki’s group at Ottawa Hospital Research Institute and the University of Ottawa has provided new insights into what we view as the critical targets for therapies in Duchenne (Dystrophin expression in muscle stem cells regulates their polarity and asymmetric division. Dumont et al., Nature Medicine 21 (12): 1455-63, 2015).  …


Added by John D. Porter, PhD on December 17, 2015 at 4:00pm — No Comments

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