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Jason Darienzo
  • 38, Male
  • Brooklyn, NY
  • United States
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Latest Activity

Jason Darienzo replied to Sarada Kuchibhotla's discussion breathing issues
"For stuffed nose my brother takes zyrtec and a nasal spray and when really congested zyrtec with decongestant.  Try using try heated humidifier attached to trilogy the cold air could cause inflammation . I use the trilogy 24/7 as a bi-pap at…"
Mar 16
Galia Ben Ishay replied to Jason Darienzo's discussion New CRISPR method efficiently corrects Duchenne muscular dystrophy defect in heart tissue
"Very interesting, thank you Jason for sharing."
Feb 7
Jason Darienzo posted a discussion

New CRISPR method efficiently corrects Duchenne muscular dystrophy defect in heart tissue

Scientists have developed a CRISPR gene-editing technique that can potentially correct a majority of the 3,000 mutations that cause Duchenne muscular dystrophy (DMD) by making a single cut at strategic points along the patient's DNA, according to a new study.https://www.sciencedaily.com/releases/2018/02/180206121017.htm…See More
Feb 6
Jason Darienzo posted a discussion
Jan 30
Jason Darienzo posted a discussion
Dec 14, 2017
Jason Darienzo posted a discussion

Rapamycin prevents age-related loss of stem cells

https://www.sciencedaily.com/releases/2017/12/171207141721.htmAdult stem cells replenish dying cells and regenerate damaged tissues throughout our lifetime. We lose many of those stem cells, along with their regenerative capacity, as we age. Working in flies and mice, researchers discovered that TOR, a nutrient sensing pathway which is central to the aging process, drives the loss of…See More
Dec 8, 2017
Jason Darienzo posted a discussion
Oct 24, 2017
Jason Darienzo replied to Jason Darienzo's discussion 'CRISPR-Gold' fixes Duchenne muscular dystrophy mutation in mice without viral vector
Oct 15, 2017
Sheila Haga Ungerer replied to Jason Darienzo's discussion 'CRISPR-Gold' fixes Duchenne muscular dystrophy mutation in mice without viral vector
"Thank you so much for sharing this.  This is VERY good to hear.  Hoping and praying this will be a huge help for so many of us!!!  "
Oct 9, 2017
Sheila Haga Ungerer replied to Jason Darienzo's discussion 'CRISPR-Gold' fixes Duchenne muscular dystrophy mutation in mice without viral vector
"Wow - Hoping and praying and hoping and praying!!  Sending so many good vibes to those scientists...possibility and hope!!!"
Oct 9, 2017
Bruce Ward replied to Jason Darienzo's discussion 'CRISPR-Gold' fixes Duchenne muscular dystrophy mutation in mice without viral vector
"This is wonderful news!   I assume it is far from practical usage.  But still wonderful news."
Oct 4, 2017
Jason Darienzo posted a discussion

'CRISPR-Gold' fixes Duchenne muscular dystrophy mutation in mice without viral vector

Scientists at the University of California, Berkeley, have engineered a new way to deliver CRISPR-Cas9 gene-editing technology inside cells and have demonstrated in mice that the technology can repair the mutation that causes Duchenne muscular dystrophy, a severe muscle-wasting disease. A new study shows that a single injection of CRISPR-Gold, as the new delivery system is called, into mice with Duchenne muscular dystrophy led to an 18-times-higher correction rate and a two-fold increase in a…See More
Oct 4, 2017
Jason Darienzo posted a discussion

Shortened telomeres linked to dysfunction in Duchenne muscular dystrophy, researchers find

Shortened telomeres linked to dysfunction in Duchenne muscular dystrophy, researchers findNew method reveals abnormally shortened telomeres in young DMD patients' muscle stem cellsA discovery about muscular dystrophy disorders has been made that suggests new possibilities for treatment. Researchers found that stem cells in the muscles of muscular dystrophy patients may, at an early age, lose their ability to regenerate new muscle, due to shortened telomeres.…See More
Sep 7, 2017
Galia Ben Ishay favorited Jason Darienzo's discussion Gene transfer corrects severe muscle defects in mice with Duchenne muscular dystrophy
Jul 28, 2017
Jason Darienzo posted a discussion

Gene transfer corrects severe muscle defects in mice with Duchenne muscular dystrophy

Gene transfer corrects severe muscle defects in mice with Duchenne muscular dystrophyDuchenne muscular dystrophy is a rapidly progressive disease that causes whole-body muscle weakness and atrophy due to deficiency in a protein called dystrophin. Researchers have developed a new gene transfer approach that uses an adeno-associated virus vector to deliver a modified dystrophin gene to muscle, restoring muscle strength in a mouse model that closely mimics the severe defects seen in patients.…See More
Jul 27, 2017
Jason Darienzo replied to Jason Darienzo's discussion Key to muscle regeneration discovered
"There is a researcher Dr. Helen Blau at Standford University that has shown stem cell depletion is a major problem and working on ways to reverse it.  However, if exon-skipping, utrophin modulation or both are started early stem cell depletion…"
Jun 15, 2017

Profile Information

About me:
I am 37 years old with DMD
About my family:
My brother Richard is 38 with DMD
Name(s) of child(ren)/individual(s) with Duchenne:
Jason Darienzo
Age(s) of child(ren)/individual(s) with Duchenne:
19 or older
City:
Brooklyn
State:
New York

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At 1:12pm on October 22, 2010, Patti Frank said…
Hey Jason, You're 30 == great. How are you doin? kevin's counsellor at MDA camp this summer (first time) is from Brooklyn too -- Angelo -- great kid. Thanks for your info. about the wc. Hope to hear back.

Patti in NJ
 
 
 

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