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Jason Darienzo
  • 38, Male
  • Brooklyn, NY
  • United States
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Latest Activity

Jason Darienzo replied to Jason Darienzo's discussion 'CRISPR-Gold' fixes Duchenne muscular dystrophy mutation in mice without viral vector
Oct 15
Sheila Haga Ungerer replied to Jason Darienzo's discussion 'CRISPR-Gold' fixes Duchenne muscular dystrophy mutation in mice without viral vector
"Thank you so much for sharing this.  This is VERY good to hear.  Hoping and praying this will be a huge help for so many of us!!!  "
Oct 9
Sheila Haga Ungerer replied to Jason Darienzo's discussion 'CRISPR-Gold' fixes Duchenne muscular dystrophy mutation in mice without viral vector
"Wow - Hoping and praying and hoping and praying!!  Sending so many good vibes to those scientists...possibility and hope!!!"
Oct 9
Bruce Ward replied to Jason Darienzo's discussion 'CRISPR-Gold' fixes Duchenne muscular dystrophy mutation in mice without viral vector
"This is wonderful news!   I assume it is far from practical usage.  But still wonderful news."
Oct 4
Jason Darienzo posted a discussion

'CRISPR-Gold' fixes Duchenne muscular dystrophy mutation in mice without viral vector

Scientists at the University of California, Berkeley, have engineered a new way to deliver CRISPR-Cas9 gene-editing technology inside cells and have demonstrated in mice that the technology can repair the mutation that causes Duchenne muscular dystrophy, a severe muscle-wasting disease. A new study shows that a single injection of CRISPR-Gold, as the new delivery system is called, into mice with Duchenne muscular dystrophy led to an 18-times-higher correction rate and a two-fold increase in a…See More
Oct 4
Jason Darienzo posted a discussion

Shortened telomeres linked to dysfunction in Duchenne muscular dystrophy, researchers find

Shortened telomeres linked to dysfunction in Duchenne muscular dystrophy, researchers findNew method reveals abnormally shortened telomeres in young DMD patients' muscle stem cellsA discovery about muscular dystrophy disorders has been made that suggests new possibilities for treatment. Researchers found that stem cells in the muscles of muscular dystrophy patients may, at an early age, lose their ability to regenerate new muscle, due to shortened telomeres.…See More
Sep 7
Galia Ben Ishay favorited Jason Darienzo's discussion Gene transfer corrects severe muscle defects in mice with Duchenne muscular dystrophy
Jul 28
Jason Darienzo posted a discussion

Gene transfer corrects severe muscle defects in mice with Duchenne muscular dystrophy

Gene transfer corrects severe muscle defects in mice with Duchenne muscular dystrophyDuchenne muscular dystrophy is a rapidly progressive disease that causes whole-body muscle weakness and atrophy due to deficiency in a protein called dystrophin. Researchers have developed a new gene transfer approach that uses an adeno-associated virus vector to deliver a modified dystrophin gene to muscle, restoring muscle strength in a mouse model that closely mimics the severe defects seen in patients.…See More
Jul 27
Jason Darienzo replied to Jason Darienzo's discussion Key to muscle regeneration discovered
"There is a researcher Dr. Helen Blau at Standford University that has shown stem cell depletion is a major problem and working on ways to reverse it.  However, if exon-skipping, utrophin modulation or both are started early stem cell depletion…"
Jun 15
Tommy B# replied to Jason Darienzo's discussion Key to muscle regeneration discovered
"Hi, I'm new. Well, not really, but I have been reading quietly the last three years.Sorry for hijacking your thread, might or might not do it again. :-B The good thing is that by now there seems to be more therapies researched than I can keep…"
Jun 15
Jason Darienzo posted a discussion
Jun 14
Jason Darienzo commented on PPMD's blog post Understanding Health Insurance Options: A Guide for People Living with Duchenne Muscular Dystrophy and their Caregivers
"Disabled children of Medicare recipients are eligible for Medicare aswell as Medicaid"
Mar 29
Jason Darienzo posted a discussion
Feb 25
Jason Darienzo replied to Sanja Kogelnik's discussion Statins and muscels
"A new therapeutic effect of simvastatin revealed by functional improvement in muscular…"
Oct 17, 2016
Jason Darienzo replied to Michael Bazant's discussion Stem cells not a sollution?
"Michael the article you posted does come off in a negative light for stem cell treatments by themselves. However, DMD will need to be treated with a combination of drugs and therapies. The article talks about muscle stem cells…"
Oct 11, 2016
Shelly favorited Jason Darienzo's discussion Sarepta Therapeutics shares jump on news of critic’s departure from FDA
Sep 21, 2016

Profile Information

About me:
I am 37 years old with DMD
About my family:
My brother Richard is 38 with DMD
Name(s) of child(ren)/individual(s) with Duchenne:
Jason Darienzo
Age(s) of child(ren)/individual(s) with Duchenne:
19 or older
City:
Brooklyn
State:
New York

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At 1:12pm on October 22, 2010, Patti Frank said…
Hey Jason, You're 30 == great. How are you doin? kevin's counsellor at MDA camp this summer (first time) is from Brooklyn too -- Angelo -- great kid. Thanks for your info. about the wc. Hope to hear back.

Patti in NJ
 
 
 

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