Share 'Exon skipping for non-sense mutations? Can it work?'
Ok i was under the impression that exon skipping would work for nonsense mutations, but I was told that it could require multiple skips to get the desired result.
Why is this so?
I thought that removing the exon with the stop codon in it would basically maintain the reading frame but without the offending exon. Arent all exons in reading frame on their own?
I do know that nonsense mutations can c…
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