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Here is the link to the parent observational study of Protandim. It was done in Europe in 2009. It looks there are positive benefits. Kind of long but you can scroll down
http://jeremybernsdorff.com/blog/uploaded/files/PDFs/Protandim_DMD_...
Let me know if you would like more info or how to order:)
"A study with MDX mice revealed that the use of ten times the human dose of Protandim in the mice for 6 months was safe and well tolerated. After 6 months of taking Protandim, 48% percent average decrease in serum TBARS was seen; 0.92nmol/mg in controlsResults: (n=9) versus 0.48 nmol/mg in Protandim® group (n=12; p=0.006). The muscle TBARS at 6 month were lower in the Protandim® treated mice. After six months, the mdx mice on control diets showed increased MRI signal abnormality (p=0.07) compared to mice on Protandim®. The use of Protandim® in this 6 month study did not significantly improve muscle strength, imaging characteristics nor histological criteria."
Interpreted - the Protandim did what it claimed in the MDX mouse ONLY, decreased serum TBARS. No trials were performed on humans with DMD. The mice showed decrease amounts of oxidative stress via a decrease in serum TBARS.
Decreasing oxidative stress is good for all of us - I would guess that decreasing oxidative is good, especially those comprimised with DMD.
Christine
We give my son Kyle (6.5 yrs) 1/2 tab of Protandim daily. I am not sure we can claim to have seen any positive effects directly attributable to Protandim. That said, we have not seen any negative effects either.
Since there are so few things that help, we are of the mindset if it may help and it doesn't hurt him we're going to give it to him - within reason of course. We are careful to never run out.
We order it off Amazon and use the www.ParentProjectMD.org/Amazon link so PPMD get's 5% of the spend back as cash. You can use the PPMD Amazon link anytime, all the time, all year, every year to help fund PPMD to find a cure. PPMD get's approx 5% of all you spend on Amazon. Tell you friends, neighbors, coworkers, etc. It's just too easy not to do it.
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