Tags:
What exactly does this mean? I was under the impression that restoring dystrophin production would restore production of nNOS... Does this say that only using that specific mini-dystrophin gene was able to restore nNOS? So, exon skipping for example, will not have the same effect?
This group is not very closed to clinical trials. As a next step, they plan to test their mini-dystrophin in dogs (if I remember correctly).
when you go into this link is reads
(last modified February 01, 2004) -is that correct?
The link was posted only to be able to see the dystrophin gene repeats at the bottom of the page. It contains description of dystrophin.
Domain sub domain amino acids exons
...
repeat 16 1992-2101 42-43
repeat 17 2102-2208 44-45
repeat 18 2209-2318 46-48
repeat 19 2319-2423 48-50
hinge 3 2424-2470 50-51
...
R Patel said:when you go into this link is reads
(last modified February 01, 2004) -is that correct?
Ofelia:
What does it mean for Jacob, if anything, who has deletions of exons 42 and 43?
Ofelia Marin said:The link was posted only to be able to see the dystrophin gene repeats at the bottom of the page. It contains description of dystrophin.
Domain sub domain amino acids exons
...
repeat 16 1992-2101 42-43
repeat 17 2102-2208 44-45
repeat 18 2209-2318 46-48
repeat 19 2319-2423 48-50
hinge 3 2424-2470 50-51
...
R Patel said:when you go into this link is reads
(last modified February 01, 2004) -is that correct?
Ofelia:
What does it mean for Jacob, if anything, who has deletions of exons 42 and 43?
Ofelia Marin said:The link was posted only to be able to see the dystrophin gene repeats at the bottom of the page. It contains description of dystrophin.
Domain sub domain amino acids exons
...
repeat 16 1992-2101 42-43
repeat 17 2102-2208 44-45
repeat 18 2209-2318 46-48
repeat 19 2319-2423 48-50
hinge 3 2424-2470 50-51
...
R Patel said:when you go into this link is reads
(last modified February 01, 2004) -is that correct?
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