What time of day do you usually take it and with what other supplements is it safe and not safe to take it with?
Has anyone got a good result with L-Arginine?
We use l-carnitine not l-arginine so I need to check that one out. I am sort of answering your question, but not as use other things to help preventr muscle pain, and so far so good as he used to complain a lot, but doesnt any more. We give Dylan aged 8 (under his paediatrican) 4000iu of Vit D twice a day and a magnesium supplement for muscle pain, also daily baths with epsom salts (magnesium phosphate). Massage with arnica oil can hel too. Regards Debbie
Not a doctor, but since our son's diagnosis I've spent a great deal of time poring over clinical evaluations of dietary supplements. L-arginine looked very promising, I read about the increase of utrophin and nnos and was cautiously excited until I saw this:
TLDR: Our findings demonstrate that arginine metabolism by arginase promotes fibrosis of muscle in muscular dystrophy and contributes to kyphosis. Our findings also show that long-term, dietary supplementation with arginine exacerbates fibrosis of dystrophic heart and muscles. Thus, commonly-practiced dietary supplementation with arginine by DMD patients has potential risk for increasing pathology when performed for long periods, despite reports of benefits acquired with short-term supplementation.
It may be worth consulting a physician on the possibility of cycling dietary arginine periodically, but given the dearth of clinical research on long term impact I would be cautious.
I have my son on an amino complex type regimen. it has arginine in it. I will ask my doctor about this. What he might say is that it is beneficial on short term use and suggest taking it for one year and then go off for a period of time and then start it again later. He says that when we use supplements, they need to be rotated because they can become non-beneficial or in some circumstances, you can overload your system and it is best to take "supplement holidays". I will have him review the article and see what he thinks. We have had our son on this regimen now for probably a year, so after his current bottle, I will take him off to see if it makes any difference just for piece of mind. I can say that we recently had our heart eval including ekg and echo and everything looked perfect and this was after he had been on the arginine for a year. hope this helps. I will let you know. thanks for posting, very interesting, and VERY helpful.