My son has had his port for a little over a year (he was in the trial). It's been relatively smooth. It freaked him out at first (he'd just gotten used to arm pokes) but infusions are no big deal now. He does have discomfort from it sometimes, particularly if he gets a bit dehydrated - so another reason to keep fluids up. If you have specific questions, feel free to contact me directly (firstname.lastname@example.org).