it is predicted that you would have to skip exon 45 to help a duplicate of 45. not sure how that would help. seems you would need to skip 44 and 45 or 45 and 46 to restore the reading frame. from what i understand, they are not yet working on skipping multiple exons...but i have been out of the loop for quite a few months now.
Amanda Rudd said:
Will exon skipping also help the duplication of 45?