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Exon deletion of 47 and 48

My son who is now 6 years old and in last may we found that his two exons has been deleted i.e. no 47 and 48. I wanted to know is there any one with same deletion. and what are they currently doing for this.

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Permalink Reply by mehrzad haidari on August 29, 2013 at 1:24am

Dear Parimal

if i am right, it seems deletion of exons 47-48 could not result in stop of dystrophin production!

if these two have been deleted, exon 46 could fit in exon 49! and no need to skip any other exons!

Please visit this to see for yourself:

http://www.muscular-dystrophy.org/about_muscular_dystrophy/research...

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Permalink Reply by Parimal Khade on August 29, 2013 at 10:16am

Do you know any clinical trial or medicine for this as exon skipping is still under trials

mehrzad haidari said:

Dear Parimal

if i am right, it seems deletion of exons 47-48 could not result in stop of dystrophin production!

if these two have been deleted, exon 46 could fit in exon 49! and no need to skip any other exons!

Please visit this to see for yourself:

http://www.muscular-dystrophy.org/about_muscular_dystrophy/research...