I am fairly new to this site but what is the situation regarding nitric oxide synthase (dystrophin associated protein), oxidative stress and muscle degeneration.
I saw this in http://www.lef.org/protocols/neurological/muscular_dystrophy_02.htm
Canadian scientists published the results of a study recently suggesting that the combination of arginine and deflazacort (a standard corticosteroid drug used in the treatment of MD) is more beneficial than deflazacort alone. Mdx mice were treated for three weeks with deflazacort, placebo, or deflazacort plus arginine. They were subsequently assessed for evidence of muscle degeneration and regeneration initiated by 24 hours of voluntary exercise. Although deflazacort alone prevented the progressive loss of function that ordinarily occurs in such mice, the deflazacort/arginine combination yielded still more impressive protection from exercise-induced muscle damage and “induced a persistent functional improvement in distance run.” According to the scientists, these results offer a new treatment option that might improve quality of life (Archer JD et al 2006).