Are you referring to the GSK exon skipping trial? Has he been in the trial? One of the known side effects of the drug is reduced coagulation. It's something they monitor throughout the trial.
I believe bleeding is not a concern at all in exon skipping trials. All side effects are getting monitored closely throughout the trial.
I would think if he was screened out of the GSK trial, he would not be a good candidate for the drug once it's commercially available unless his coagulation numbers were watched very carefully. My son is in the GSK trial in France (we're in the UK but moved here last year from the US). They take blood coagulation very seriously.
You can correct those right? Can you treat and get those levels in range? If you can, then I see no problem to use the GSK drug if approved. The AVI drug doesn't have those side effects, hence he can use it if ever approved. These drugs are years away from approval so I would consult doctors to get those levels in range if possible.
We are going to the Portland Demand V trial site. We had hope when our local children's hospital hematologist repeated the labs and the PT was normal, fibrinogen above the cutoff. Then we went back to portland, got blood redrawn, and at GSK's labs the pt was just barely qualifying and fibrinogen was still low. Now waiting for hemalogist and neurologist to connect, but we're pretty discouraged. I'm hoping this is an error with GSK's lab, but would be surprised if they admit that. Dang.