This is the AVI presentation from this morning:
http://www.wsw.com/webcast/maxim3/avii/
Not much news. The Phase 2 placebo controlled double blind clinical trial testing 50 and 100 mg/kg dose levels is ready to start (subject to FDA approval of the protocol and IRB approval) at Nationwide Childrens Hospital in Columbus OH. Principal investigators: Drs. Jerry Mendell and Kevin Flanigan.
I'll attach a slide I created with the relevant stuff presented about AVI-4658. I love that picture on slide 14! He also quoted Dr. Muntoni who said that the biopsies from the UK trial started to look as non-DMD biopsies.
Tags:
I forgot to add that he mentioned twice NO immune response observed and reduction in CD3, CD4, CD8 inflammatory markers (meaning disease modification) observed in the UK trial.
Has there been any indications as to why they are getting no immune response? I dont work on the immunology side of science, but I understand the basica concepts, yet I find it confusing as to what is and isnt casuing immune responses in different studies.
Ofelia Marin said:I forgot to add that he mentioned twice NO immune response observed and reduction in CD3, CD4, CD8 inflammatory markers (meaning disease modification) observed in the UK trial.
© 2022 Created by PPMD.
Powered by
Badges | Report an Issue | Privacy Policy | Terms of Service